Mobile-based Skin Lesions Classification Using Convolution Neural Network

This research work is aimed at investing skin lesions classification problem using Convolution Neural Network (CNN) using cloud-server architecture. Using the cloud services and CNN, a real-time mobile-enabled skin lesions classification expert system “i-Rash” is proposed and developed. i-Rash aimed at early diagnosis of acne, eczema and psoriasis at remote locations. The classification model used in the “i-Rash” is developed using the CNN model “SqueezeNet”. The transfer learning approach is used for training the classification model and model is trained and tested on 1856 images. The benefit of using SqueezeNet results in a limited size of the trained model i.e. only 3 MB. For classifying new image, cloud-based architecture is used, and the trained model is deployed on a server. A new image is classified in fractions of seconds with overall accuracy, sensitivity and specificity of 97.21%, 94.42% and 98.14% respectively. i-Rash can serve in initial classification of skin lesions, hence, can play a very important role early classification of skin lesions for people living in remote areas

Assay Type Detection Using Advanced Machine Learning Algorithms

The colourimetric analysis has been used in diversified fields for years. This paper provides a unique overview of colourimetric tests from the perspective of computer vision by describing different aspects of a colourimetric test in the context of image processing, followed by an investigation into the development of a colorimetric assay type detection system using advanced machine learning algorithms. To the best of our knowledge, this is the first attempt to define colourimetric assay types from the eyes of a machine and perform any colorimetric test using deep learning. This investigation utilizes the state-of-the-art pre-trained models of Convolutional Neural Network (CNN) to perform the assay type detection of an enzyme-linked immunosorbent assay (ELISA) and lateral flow assay (LFA). The ELISA dataset contains images of both positive and negative samples, prepared for the plasmonic ELISA based TB-antigen specific antibody detection. The LFA dataset contains images of the universal pH indicator paper of eight pH levels. It is noted that the pre-trained models offered 100% accurate visual recognition for the assay type detection. Such detection can assist novice users to initiate a colorimetric test using his/her personal digital devices. The assay type detection can also aid in calibrating an image-based colorimetric classification

Clustering and Classification of a Qualitative Colorimetric Test

In this paper, we present machine learning based detection methods for a qualitative colorimetric test. Such an automatic system on mobile platform can emancipate the test result from the color perception of individuals and its subjectivity of interpretation, which can help millions of populations to access colorimetric test results for healthcare, allergen detection, forensic analysis, environmental monitoring and agricultural decision on point-of-care platforms. The case of plasmonic enzyme-linked immunosorbent assay (ELISA) based tuberculosis disease is utilized as a model experiment. Both supervised and unsupervised machine learning techniques are employed for the binary classification based on color moments. Using 10-fold cross validation, the ensemble bagged tree and k-nearest neighbors algorithm achieved 96.1% and 97.6% accuracy, respectively. The use of multi-layer perceptron with Bayesian regularization backpropagation provided 99.2% accuracy. Such high accuracy system can be trained off-line and deployed to mobile devices to produce an automatic colourimetric diagnostic decision anytime anywhere

An intelligent mobile-enabled expert system for tuberculosis disease diagnosis in real time

This paper presents an investigation into the development of an intelligent mobile-enabled expert system to perform an automatic detection of tuberculosis (TB) disease in real-time. One third of the global population are infected with the TB bacterium, and the prevailing diagnosis methods are either resource-intensive or time consuming. Thus, a reliable and easy–to-use diagnosis system has become essential to make the world TB free by 2030, as envisioned by the World Health Organisation. In this work, the challenges in implementing an efficient image processing platform is presented to extract the images from plasmonic ELISAs for TB antigen-specific antibodies and analyse their features. The supervised machine learning techniques are utilised to attain binary classification from eighteen lower-order colour moments. The proposed system is trained off-line, followed by testing and validation using a separate set of images in real-time. Using an ensemble classifier, Random Forest, we demonstrated 98.4% accuracy in TB antigen-specific antibody detection on the mobile platform. Unlike the existing systems, the proposed intelligent system with real time processing capabilities and data portability can provide the prediction without any opto-mechanical attachment, which will undergo a clinical test in the next phase.</p

Intelligent image-based colourimetric tests using machine learning framework for lateral flow assays

This paper aims to deliberately examine the scope of an intelligent colourimetric test that fulfils ASSURED criteria (Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment-free, and Deliverable) and demonstrate the claim as well. This paper presents an investigation into an intelligent image-based system to perform automatic paper-based colourimetric tests in real-time to provide a proof-of-concept for a dry-chemical based or microfluidic, stable and semi-quantitative assay using a larger dataset with diverse conditions. The universal pH indicator papers were utilised as a case study. Unlike the works done in the literature, this work performs multiclass colourimetric tests using histogram based image processing and machine learning algorithm without any user intervention. The proposed image processing framework is based on colour channel separation, global thresholding, morphological operation and object detection. We have also deployed a server based convolutional neural network framework for image classification using inductive transfer learning on a mobile platform. The results obtained by both traditional machine learning and pre-trained model-based deep learning were critically analysed with the set evaluation criteria (ASSURED criteria). The features were optimised using univariate analysis and exploratory data analysis to improve the performance. The image processing algorithm showed >98% accuracy while the classification accuracy by Least Squares Support Vector Machine (LS- SVM) was 100%. On the other hand, the deep learning technique provided >86% accuracy, which could be further improved with a large amount of data. The k-fold cross validated LS- SVM based final system, examined on different datasets, confirmed the robustness and reliability of the presented approach, which was further validated using statistical analysis. The understaffed and resource limited healthcare system can benefit from such an easy-to-use technology to support remote aid workers, assist in elderly care and promote personalised healthcare by eliminating the subjectivity of interpretation

Cyber attacks, countermeasures, and protection schemes — A state of the art survey

Thousands of cyber-attacks (fraudulent online activities to acquire users’ sensitive information via email, during online transactions, live video streaming, online gaming and browsing) are launched every day against Internet users across the world. To prevent these attacks, researchers have responded with a number of protection systems. Currently, the methods which cyber-attackers use to conduct attacks is associated with exploiting humans. Such attacks are recorded more frequently than before, and they are more challenging to control. Traditional security countermeasures are unable to prevent breaches targeting the human element. This paper describes the state of the art of cyber security attacks, countermeasures, and protection tools related to everyday online activities. It provides a useful cyber-attack taxonomy and classification which helps to involve in a protection process to identify attacks and measures for cyber security. Existing protection schemes that target the cyber threats and risks are evaluated against three of our criteria for an effective measure: resilience to cyber-attacks’ countermeasures; real-time support and needs-based action; and training and educational materials to increase users’ awareness of cybercrimes. Potential features of smart solutions to cybercrime are also identified

A Brain-Inspired Trust Management Model to Assure Security in a Cloud Based IoT Framework for Neuroscience Applications

Rapid advancement of Internet of Things (IoT) and cloud computing enables neuroscientists to collect multilevel and multichannel brain data to better understand brain functions, diagnose diseases, and devise treatments. To ensure secure and reliable data communication between end-to-end (E2E) devices supported by current IoT and cloud infrastructures, trust management is needed at the IoT and user ends. This paper introduces an adaptive neuro-fuzzy inference system (ANFIS) brain-inspired trust management model (TMM) to secure IoT devices and relay nodes, and to ensure data reliability. The proposed TMM utilizes both node behavioral trust and data trust, which are estimated using ANFIS, and weighted additive methods respectively, to assess the nodes trustworthiness. In contrast to existing fuzzy based TMMs, simulation results confirm the robustness and accuracy of our proposed TMM in identifying malicious nodes in the communication network. With growing usage of cloud based IoT frameworks in Neuroscience research, integrating the proposed TMM into existing infrastructure will assure secure and reliable data communication among E2E devices